Process for preparing a charcoal-gm1 complex

Details Process for preparing a charcoal-gm1 complex Process for preparing a charcoal-gm1 complex

C - Chemistry, Metallurgy

07

H

C07H 15/10 (2006.01) A61K 31/70 (2006.01) A61K 47/48 (2006.01) A61P 31/04 (2006.01) C07H 1/06 (2006.01)

Patent

CA 2380481

The invention provides a process to prepare a complex of adsorption charcoal- GM1 stable at different pH values. This process is based on the suspension method, the formulation example being presented. An analytical method to determine non derivatized GM1 in aqueous solutions using the high efficiency liquid chromatography technique is also object of the present inven-tion.

L'invention concerne un procédé de préparation d'un complexe de charbon adsorbant-GM1, stable à des pH de valeur différente. Ce procédé repose sur la méthode de suspension, dont un exemple de formulation est décrit. L'invention concerne également une méthode analytique de détermination de GM1 non modifié, dans des solutions aqueuses, au moyen d'une technique de chromatographie en phase liquide haute performance.

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