Stabilizing formulations

Details Stabilizing formulations Stabilizing formulations

G - Physics

01

N

G01N 33/531 (2006.01)

Patent

CA 2575870

Formulations are described that are suitable for storage of proteins, such as antibodies, over a relatively broad range of protein concentrations, pH, and buffer types. Also described are methods of storing a protein and methods of identifying a suitable formulation for storage of a specific protein. In general, a formulation contains low to no surfactant, no to relatively low salt concentrations, and requires a relatively low buffer concentration.

La présente invention se rapporte à des préparations permettant de conserver des protéines, telles que des anticorps, avec une gamme relativement large de teneurs en protéines, de pH et de types de solutions tampons. L'invention a également trait à des procédés de conservation d'une protéine, et à des procédés d'identification d'une préparation permettant de conserver une protéine spécifique. En général, une préparation selon l'invention contient une quantité faible à nulle de tensioactif, une teneur en sel nulle à relativement faible, et nécessite une teneur en solution tampon relativement faible.

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