Antitumor mitoxantrone polymeric compositions

A - Human Necessities – 61 – K

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A61K 47/48 (2006.01) A61K 31/135 (2006.01) A61K 31/136 (2006.01) A61K 31/415 (2006.01) A61K 31/4168 (2006.01) A61K 47/32 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2119675

ABSTRACT An antitumor polymeric composition comprising an anthracene antitumor compound, particularly mitoxantrone, covalently conjugated to, or admixed with, a divinyl ether-maleic anhydride (MVE) copolymer and methods of treating solid tumors and inducing regression of leukemia cell growth in mammals by administering such compositions.

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