Processes for the production of (+)-"nal" morphinan compounds

Details Processes for the production of (+)-"nal" morphinan compounds Processes for the production of (+)-"nal" morphinan compounds

C - Chemistry, Metallurgy

07

D

C07D 489/08 (2006.01)

Patent

CA 2709886

The invention generally provides processes and intermediate compounds useful for the production of (+) nal morphinan compounds. In particular, the process encompasses synthetic routes for the production of (+) nal morphinan compounds or derivatives of (+) nal morphinan compounds from (+)-morphinan substrates such as (+)-hydrocodone, (+)-norhydrocodone or derivatives of either compound.

L'invention porte d'une manière générale sur des procédés et des composés intermédiaires utiles pour la production de composés de morphinane de type (+)-nal. En particulier, le procédé comprend des voies de synthèse pour la production de composés de morphinane de type (+)-nal ou de dérivés de composés de morphinane de type (+)-nal à partir de substrats de (+)-morphinane tels que la (+)-hydrocodone, la (+)-norhydrocodone ou les dérivés de l'un ou l'autre composé.

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