Composition and method for potentiating drugs

A - Human Necessities – 61 – K

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A61K 31/79 (2006.01) A61K 31/047 (2006.01) A61K 31/137 (2006.01) A61K 31/165 (2006.01) A61K 31/4045 (2006.01) A61K 31/721 (2006.01) A61K 31/765 (2006.01) A61K 45/06 (2006.01) A61P 25/00 (2006.01)

Patent

CA 2437351

A method of potentiating the activity of a drug which affects the central nervous system (CNS) comprising systemically administrating to a subject said drug together with an effective amount of a compound which affects peripheral chemoreceptors and, optionally, with an effective amount of a stimulator of osmoreceptors. Also disclosed are pharmaceutical compositions for systemic administration comprising a CNS drug together with the aforementioned compounds.

Cette invention concerne une méthode permettant de potentialiser l'activité d'un médicament qui agit sur le système nerveux central. Cette méthode consiste à administrer systématiquement ledit médicament à un sujet, conjointement avec une dose efficace d'un composé qui agit sur les chimiorécepteurs et, éventuellement, une dose efficace d'un stimulateur des récepteurs osmotiques. Sont également décrites des compositions pharmaceutiques pour administration systémique qui renferment un médicament du système nerveux central ainsi que les composés susmentionnés.

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