C - Chemistry – Metallurgy – 07 – F
Patent
C - Chemistry, Metallurgy
07
F
C07F 9/6539 (2006.01) A61K 31/33 (2006.01) A61K 31/675 (2006.01) C07D 271/06 (2006.01) C07D 277/28 (2006.01) C07D 277/30 (2006.01) C07D 413/06 (2006.01) C07D 417/06 (2006.01) C07F 9/58 (2006.01) C07F 9/653 (2006.01) C07F 9/655 (2006.01) C07F 9/6553 (2006.01) C07F 9/6558 (2006.01)
Patent
CA 2319493
This invention concerns compounds for inhibiting intracellular signal transduction, especially intracellular signal transduction mediated by one or more molecular interactions involving a phosphotyrosine-containing protein. This invention also relates to pharmaceutical compositions containing the compounds and prophylactic and therapeutic methods involving pharmaceutical and veterinary administration of the compounds. The compounds are of formula (I) as defined herein.
L'invention porte sur des composés inhibiteurs de la transduction de signaux intracellulaires et en particulier de la transduction de signaux induits par une ou plusieurs interactions impliquant une protéine contenant de la phosphotyrosine. L'invention porte également sur des compositions pharmaceutiques contenant lesdits composés et sur des méthodes prophylactiques et thérapeutiques recourant à l'administration pharmaceutique ou vétérinaire desdits composés. Ces composés sont de formule (I).
Bohacek Regine
Buchanan John L.
Luke George P.
Vu Chi B.
Ariad Pharmaceuticals Inc.
Borden Ladner Gervais Llp
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