Density enhanced protein tyrosine phosphatases

Details Density enhanced protein tyrosine phosphatases Density enhanced protein tyrosine phosphatases

C - Chemistry, Metallurgy

12

N

C12N 15/55 (2006.01) C07K 16/40 (2006.01) C12N 5/10 (2006.01) C12N 9/16 (2006.01) C12Q 1/42 (2006.01) C12Q 1/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2166479

Novel Type III density enhanced protein tyrosine phosphatases are disclosed and exemplified by human DEP-1 enzyme. Polynucleotides, encoding huDEP-1 are disclosed, along with methods and materials for production of the same by recombinant procedures. Binding molecules specific for DEP-1 are also disclosed as useful for modulating the biological activities of DEP-1.

L'invention porte sur de nouvelles tyrosine phosphatases de type III à densité renforcée dont l'enzyme humaine DEP-1 est un exemple. L'invention porte également sur des polynucléotides codant pour la DEP-1 humaine et sur des méthodes et matériaux servant à la reproduire par recombinaison. Elle porte en outre sur des molécules fixatrices spécifiques à la DEP-1 et servant à en moduler les activités biologiques.

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