Ophthalmic compositions for treating ocular hypertension

Details Ophthalmic compositions for treating ocular hypertension Ophthalmic compositions for treating ocular hypertension

C - Chemistry, Metallurgy

07

D

C07D 209/88 (2006.01) A61K 31/403 (2006.01) A61K 31/427 (2006.01) A61K 31/4709 (2006.01) A61P 27/06 (2006.01) C07D 401/06 (2006.01) C07D 403/06 (2006.01) C07D 417/06 (2006.01)

Patent

CA 2583593

This invention relates to potent potassium channel blocker compounds of Formula (I) or a formulation thereof for the treatment of glaucoma and other conditions which leads to elevated intraoccular pressure in the eye of a patient. This invention also relates to the use of such compounds to provide a neuroprotective effect to the eye of mammalian species, particularly humans.

L'invention concerne des composés de formule (I), qui constituent de puissants inhibiteurs des canaux potassiques, ou une formulation de ces composés, servant à traiter les glaucomes et d'autres états qui engendrent une pression intraocculaire élevée dans l'oeil d'un patient. Cette invention se rapporte en outre à l'utilisation de ces composés pour exercer une action neuroprotectrice sur l'oeil d'espèces mammaliennes, en particulier d'êtres humains.

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