Monoclonal antibodies for small moieties, methods therefor

C - Chemistry – Metallurgy – 12 – P

Patent

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Details

C12P 21/08 (2006.01) A61K 39/395 (2006.01) C07K 16/44 (2006.01) C12N 5/16 (2006.01) G01N 33/543 (2006.01) G01N 33/577 (2006.01) G01N 33/68 (2006.01) G01N 33/84 (2006.01)

Patent

CA 2047717

The invention is directed to monoclonal antibodies, their fragments, single chains and polypeptide mimics of their hyper-variable regions which immunoreact with bare small moieties such as metallic canons and small organic molecules, the hybridomas for production of the monoclonal antibodies, immunogen compounds for developing the hybridomas, and methods for use of the monoclonal antibodies.

L'invention concerne des anticorps monoclonaux, leurs fragments, des chaînes individuelles et des imitateurs polypeptidiques de leurs régions hypervariables immuniréagissant avec des petites fractions simples telles que des cations métalliques et des petites molécules organiques, les hybridomes permettant la production des anticorps monoclonaux, des composés immunogènes permettant de développer les hybridomes, ainsi que des procédés d'utilisation des anticorps monoclonaux.

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