Substituted 4,6-di-tertiary-butyl-5-hydroxy-pyrimidines

Details Substituted 4,6-di-tertiary-butyl-5-hydroxy-pyrimidines Substituted 4,6-di-tertiary-butyl-5-hydroxy-pyrimidines

C - Chemistry, Metallurgy

07

D

C07D 239/34 (2006.01)

Patent

CA 2365269

The present invention is novel compounds having the following general formula: (see formula I) wherein: Me is CH3; Q' is hydrogen or a protecting group; and Q" is CHNOH, CN, CO2H, CSNH2, or (see formula II), CHO, COOR20 wherein R20 is lower alkyl. The invention is a precursor in the preparation of pharmaceutical compounds which are inhibitors of 5- lipoxygenase and/or cyclooxygenase and therefore useful in treating inflammation and related disorders.

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