Tocopherol derivatives

Details Tocopherol derivatives Tocopherol derivatives

C - Chemistry, Metallurgy

07

K

C07K 5/027 (2006.01) C07D 311/72 (2006.01) C07D 405/12 (2006.01) C07K 4/00 (2006.01) A61K 7/42 (1995.01)

Patent

CA 2148148

This invention provides a tocopherol derivative of the following formula (I) or a pharmacologically acceptable salt thereof Image (I) wherein R1 and R2 are the same or different and each represents hydrogen or methyl; R3 represents an .alpha. - amino acid, .omega. -amino acid, or peptide bonding via the N terminus thereof, except that in the case of cysteine or glutathione which has a thiol group, bonding via the thiol group. The tocopherol derivative of this invention is a compound which is water- soluble and can be expected to be of use as a cerebral function-improving drug and an anticataract drug. Moreover, this compound is of value as an UV-absorber,a skin care ingredient, or a stabilizer for other cosmetic ingredients.

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