Reagents, methods and kits for an amphetamine-class...

Details Reagents, methods and kits for an amphetamine-class... Reagents, methods and kits for an amphetamine-class...

C - Chemistry, Metallurgy

07

D

167/43, 530/15.1

C07D 311/82 (2006.01) A61K 39/385 (2006.01) C07D 405/12 (2006.01) C07K 14/765 (2006.01) G01N 33/53 (2006.01) G01N 33/533 (2006.01) G01N 33/542 (2006.01) G01N 33/94 (2006.01)

Patent

CA 2014318

A fluorescent polarization immunoassay(FPIA) for detecting the presence of one or more amphetamine-class analytes in a test sample is provided. The immunoassay uses competition between the analyte and a fluorescently labeled tracer for the binding site on an antibody specific for phenethylamine derivatives. The concentration of amphetamine-class analyte in the sample determines the amount of tracer that binds to the antibody. The amount of tracer/antibody complex formed can be quantitatively measured and is inversely proportional to the quantity of analyte in the test sample. The invention relates to tracers, to immunogens used to elicit antibodies for use as assay reagents, and to assay kits incorporating these tracers and assay reagents. The tracers have the following general formula: Image wherein R1, R2, and R4 are hydrogen, R3 is methyl, and R5 is MFI, wherein FI is fluorescein or ,a fluorescein derivative, and M is a linking group consisting of form 0 to 15 carbon atoms and heteroatoms, including not more than six heteroatoms, arranged in a straight or branched chain, saturated or unsaturated, with the proviso that not more than two heteroatoms are linked in sequence and that branchings may occur only on carbon atoms, wherein said heteroatoms are selected from nitrogen and oxygen.

Affiliated with

Also associated with

Rating

Reagents, methods and kits for an amphetamine-class... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Reagents, methods and kits for an amphetamine-class..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Reagents, methods and kits for an amphetamine-class... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1643406