Substituted piperazine compounds

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 295/15 (2006.01)

Patent

CA 2657986

Novel compounds of the general formula: (see formula above) and pharmaceutically acceptable acid addition salts thereof, wherein the compounds are useful in therapy to protect skeletal muscles against damage resulting from trauma or to protect skeletal muscles subsequent to muscle or systemic diseases such as intermittent claudication, to treat shock conditions, to preserve donor tissue and organs used in transplants, in the treatment of cardiovascular diseases including atrial and ventricular arrhythmias, Prinzmetal's (variant) angina, stable angina, and exercise induced angina, congestive heart disease, and myocardial infarction.

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