Pgds as modifiers of the pten pathway and methods of use

Details Pgds as modifiers of the pten pathway and methods of use Pgds as modifiers of the pten pathway and methods of use

G - Physics

01

N

G01N 33/53 (2006.01)

Patent

CA 2570483

Human PGD genes are identified as modulators of the PTEN pathway, and thus are therapeutic targets for disorders associated with defective PTEN function. Methods for identifying modulators of PTEN, comprising screening for agents that modulate the activity of PGD are provided.

Selon cette invention, les gène PGD humains sont identifiés comme étant des modulateurs de la voie PTEN et constituent par conséquent des cibles thérapeutiques pour des troubles associés à une fonction PTEN défective. Cette invention concerne également des méthodes permettant d'identifier des modulateurs de PTEN et comprenant notamment le criblage d'agents qui modulent l'activité de la PGD.

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