Caml-binding peptides

Details Caml-binding peptides Caml-binding peptides

C - Chemistry, Metallurgy

12

N

C12N 15/11 (2006.01) A61K 38/04 (2006.01) C07K 14/065 (2006.01) C07K 14/075 (2006.01) C07K 14/47 (2006.01) C07K 14/705 (2006.01) C12N 15/62 (2006.01)

Patent

CA 2430948

This invention provides peptides that bind to CAML, and nucleic acids encoding such peptides. These peptides and nucleic acids are useful for targeting CAML and for modulating of CAML activity so as to affect immune or inflammatory response or to evade apoptosis. Also provided are vectors for expressing such peptides and implantable medical devices comprising the peptides or nucleic acids.

L'invention concerne des peptides se liant avec le ligand CAML, et des acides nucléiques codant lesdits peptides. Les peptides et les acides nucléiques en question sont utiles pour le ciblage du ligand CAML et pour la modulation de son activité, de manière à affecter la réponse immune ou inflammatoire ou à éviter l'apoptose. L'invention concerne également des vecteurs pour l'expression de ces peptides et des dispositifs médicaux implantables renfermant les peptides ou les acides nucléiques considérés.

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