Storage stable extended release oral dosage composition...

A - Human Necessities – 61 – K

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A61K 31/4545 (2006.01) A61K 9/24 (2006.01) A61K 31/137 (2006.01) A61K 31/445 (2006.01) A61K 31/473 (2006.01) A61P 11/02 (2006.01) A61K 9/20 (2006.01) A61K 47/02 (2006.01) A61K 47/12 (2006.01) A61K 47/18 (2006.01)

Patent

CA 2329172

A compressed bilayer solid composition comprising (a) an immediate release first layer comprising an anti-allergic effective amount of desloratadine and at least one pharmaceutically acceptable excipient and (b) a sustained release second layer comprising an effective amount of a nasal decongestant and a pharmaceutically acceptable sustained release agent wherein the composition contains less than about 2 % of desloratadine decomposition products is disclosed.

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