Substance exhibiting antidepressant property

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/4015 (2006.01) A61P 25/24 (2006.01) C07D 207/263 (2006.01)

Patent

CA 2521923

The invention relates to medicine, more specifically to antidepressant pharmacology which selectively improves a diminished mood dominated by asthenic emotions. The inventive antidepressant substance is embodied in the form of N-carbamoyl-methyl-4-phenyl-2-pyrrolidone. Said invention increases the evidence of antidepressant effect after a single dose, prevents sedative and cholinergic effects, avoids the development of a tolerance and withdrawal syndrome during a course of application and allows for the unrestricted use of said substance for professional activity.

L'invention appartient au domaine de la médecine et notamment de la pharmacologie et concerne des produits antidépressifs qui améliorent de manière sélective les états d'humeur dépressive dominés par des émotions à caractère asthénique. On utilise en tant que substance possédant une activité nootrope le N-carbamoyl-méthyl-4-phényl-2-pyrrolidone. L'invention permet d'obtenir un effet antidépressif exprimé de façon plus prononcée après une seule prise, d'éviter les effets sédatif et cholinolytique, d'éviter l'accoutumance et le syndrome de manque lors d'un traitement systémique; en outre, il n'existe pas de limitations lors d'une administration par des professionnels de la santé.

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