Optical resolution method

Details Optical resolution method Optical resolution method

C - Chemistry, Metallurgy

07

C

C07C 37/86 (2006.01) C07B 55/00 (2006.01) C07B 57/00 (2006.01) C07C 29/92 (2006.01) C07C 31/20 (2006.01) C07C 39/14 (2006.01) C07C 39/38 (2006.01) C07C 51/487 (2006.01) C07C 65/11 (2006.01) C07C 67/60 (2006.01) C07C 69/94 (2006.01) C07C 209/88 (2006.01) C07C 211/09 (2006.01) C07C 249/14 (2006.01) C07C 251/48 (2006.01)

Patent

CA 2048286

ABSTRACT OF THE DISCLOSURE The present invention provides three optical resolution methods. The first aspect comprises the steps of adding an optically active bifunctional resolving reagent to a bifunctional compound to form a liquid material, precipitating crystals therefrom, treating the crystals and the liquid material separately with an acidic material, a basic material, or a basic material and an acidic material, to obtain a pair of enantiomers of an optically active bifunctional compound. The second aspect comprises an optical resolution method by which one necessary enantiomer of a pair of enantiomers in an optically active bifunctional compound is exclusively obtained. The third aspect comprises a method for racemizing one unnecessary enantiomer of a pair of enantiomers in an optically active bifunctional compound which is formed by the optical resolution method of the present invention.

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