Processes for the preparation of...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 223/16 (2006.01)

Patent

CA 2646044

The present invention provides processes, methods and intermediates for the preparation of 8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine, salts, hydrates and crystal forms thereof which are useful as serotonin (5-HT) receptor agonists for the treatment of, for example, central nervous system disorders such as obesity.

Cette invention concerne des procédés, et des produits intermédiaires permettant de préparer du 8-chloro-1-méthyl-2,3,4,5-tétrahydro-1H-3-benzazépine, des sels, des hydrates et des formes cristallines de ce composant, utiles en tant qu'agonistes du récepteur (5-HT) de la sérotonine pour le traitement, par exemple, de troubles du système nerveux central, tels que l'obésité.

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