Hybrid calcitonin

Details Hybrid calcitonin Hybrid calcitonin

C - Chemistry, Metallurgy

07

K

C07K 19/00 (2006.01) C07K 1/00 (2006.01) C07K 14/585 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2080233

-43- HYBRID CALCITONIN ABSTRACT OF THE DISCLOSURE The improved hybrid calcitonin consists of a peptide segment in human calcitonin and a peptide segment in calcitonin derived from animals other than humans, such as eel, salmon and chicken. Each of the human or human analog calcitonins and the calcitonins derived from animals other than humans may be either native calcitonin or an analog thereof. The hybrid calcitonin has the outstanding advantage that it exhibits biological activities as strong as eel, salmon and chicken calcitonin while causing no side effects including nausea, disorders in the functions of the digestive tract or antigenicity.

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