Therapeutic agent for corneal/conjuctival disease

A - Human Necessities – 61 – K

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Details

A61K 31/4178 (2006.01) A61K 9/06 (2006.01) A61K 9/08 (2006.01) A61P 27/02 (2006.01)

Patent

CA 2631231

The object is to discover a novel use of eprosartan or a salt thereof. Eprosartan or a salt thereof shows excellent ameliorating activity in a corneal disorder model, and therefore is useful as a therapeutic agent for a corneal/conjunctival disorder such as dry eye, corneal ulcer, keratitis, conjunctivitis, superficial punctuate keratopathy, corneal epithelial defect, conjunctival epithelial defect, keratoconjunctivitis sicca, superior limbic keratoconjunctivitis and filamentary keratitis.

La présente invention concerne une utilisation atypique d~eprosartan ou un sel dérivé. L~eprosartan ou un sel dérivé démontre une activité excellente d~amélioration de modèle de trouble cornéen et il est par conséquent utile comme agent thérapeutique du trouble cornéen/conjonctival tel que sécheresse oculaire, ulcère de la cornée, kératite, conjonctivite, kératopathie ponctuée superficielle, trouble épithélial de la cornée, trouble épithélial conjonctif, kéraconjonctivite sèche, kéraconjonctivite limbique supérieure et kératite filamentaire.

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