Conserved hemagglutinin epitope, antibodies to the epitope,...

C - Chemistry – Metallurgy – 07 – K

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C07K 14/11 (2006.01) A61K 39/145 (2006.01) A61K 39/385 (2006.01) A61K 39/42 (2006.01) C07K 16/10 (2006.01) C07K 17/00 (2006.01) C07K 19/00 (2006.01)

Patent

CA 2736799

Disclosed are antibodies that bind to the stem region of influenza hemagglutinin in the neutral pH conformation, hemagglutinin epitopes in the stem region, and methods of making and using both.

L'invention concerne des anticorps qui se lient à la région de tige de l'hémagglutinine du virus influenza dans la conformation à pH neutre, des épitopes d'hémagglutinine dans la région de tige, et des procédés pour préparer et utiliser ces composés.

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