Remedy for diseases caused by il-6 production

A - Human Necessities – 61 – K

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A61K 39/395 (2006.01) A61P 7/06 (2006.01) A61P 13/12 (2006.01)

Patent

CA 2203182

Pharmaceutical compositions for prevention or treatment of diseases caused by interleukin-6 production, comprising an antibody to interleukin-6 receptor (IL-6R antibody). As the IL-6R antibody, an antibody of animals other than the human such as mice, rats, etc., a chimeric antibody between these and a human antibody, a reshaped human antibody, etc. may be used. The pharmaceutical compositions are useful for prevention or treatment of diseases caused by interleukin-6 production such as plasmacytosis, anti-IgG1-emia; anemia, nephritis, etc.

Agent préventif ou remède contre des maladies provoquées par la production d'interleukine-6, contenant un anticoprs contre des récepteurs à l'interleukine-6 (un anticorps anti IL-6R). On peut citer à titre d'exemples de l'anticorps des anticorps d'animaux tels que la souris et le rat, des anticorps chimères comprenant les anticorps précités ainsi qu'un anticorps humain, et un anticorps humain reconstitué. On peut citer à titre d'exemples des maladies concernées la plasmacytose, l'anti-IgG1-émie, l'anémie et la néphrite.

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