Process for constructing a cdna library and a novel...

C - Chemistry – Metallurgy – 07 – K

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C07K 14/47 (2006.01) A61K 38/17 (2006.01) A61K 39/395 (2006.01) C07K 16/18 (2006.01) C12N 15/12 (2006.01) C12N 15/63 (2006.01) C40B 50/06 (2006.01)

Patent

CA 2381458

A process for constructing a cDNA library which has a selectivity for signal peptides, that makes it possible to efficiently identify unknown and useful polypeptide comprising a signal peptide. A novel polypeptide consisting of 89 amino acids (including a signal peptide) produced by a stroma cell line, which is useful as an agent far preventing or treating, for example, anemia, leukopenia or infections and the like, and DNAs coding for said polypeptide, have been identified using the process of the invention.

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