Methods for the detection of preeclampsia

G - Physics – 01 – N

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G01N 33/50 (2006.01) C12M 1/00 (2006.01) C12Q 1/32 (2006.01) C12Q 1/527 (2006.01) C12Q 1/533 (2006.01) C12Q 1/68 (2006.01) C40B 30/00 (2006.01) C40B 30/04 (2006.01) C40B 40/00 (2006.01) C40B 40/10 (2006.01) G01N 33/573 (2006.01) G01N 33/68 (2006.01) G01N 33/92 (2006.01)

Patent

CA 2723322

Biomarkers associated with preeclampsia were identified. Nine proteins were identified as being differentially regulated between the control and the under 28-weeks preeclamptic samples. Similarly three proteins were identified as being differentially regulated between the control and the over 28-weeks preeclamptic samples. These 12 proteins can be used as potential biomarkers in the diagnosing and prognosing of preeclampsia.

On a identifié des biomarqueurs associés à la prééclampsie, ainsi que neuf protéines qui ont été identifiées comme ayant une régulation différentielle entre le témoin et les échantillons prééclamptiques à moins de 28 semaines. De même, on a identifié trois protéines comme présentant une régulation différentielle entre le témoin et les échantillons prééclamptiques à plus de 28 semaines. Ces 12 protéines peuvent être utilisées en tant que biomarqueurs potentiels dans le diagnostic et le pronostic de la prééclampsie.

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