Long-acting y2 and/or y4 receptor agonists

Details Long-acting y2 and/or y4 receptor agonists Long-acting y2 and/or y4 receptor agonists

C - Chemistry, Metallurgy

07

K

C07K 14/575 (2006.01) A61K 38/17 (2006.01)

Patent

CA 2723855

The present invention relates to a PYY or PP peptide derivative or analogue thereof derivatised with one or more serum albumin binding side chains comprising a dis-tal tetrazole or carboxylic acid group. Moreover, the invention relates to compositions hereof and methods of treatment of conditions responsive to Y receptor modulation.

La présente invention concerne un dérivé de peptide PYY ou PP ou un analogue de celui-ci avec une ou plusieurs chaînes latérales de liaison de sérum-albumine comprenant un groupe tétrazole ou acide carboxylique distal. De plus, linvention concerne des compositions de celui-ci et des procédés de traitement de pathologies répondant à la modulation  du récepteur Y.

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