Antisense modulation of survivin expression

Details Antisense modulation of survivin expression Antisense modulation of survivin expression

C - Chemistry, Metallurgy

07

H

C07H 21/04 (2006.01) A61K 48/00 (2006.01) C12N 15/00 (2006.01) C12N 15/09 (2006.01) C12N 15/11 (2006.01) C12Q 1/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2398889

Antisense compounds, compositions and methods are provided for modulating the expression of Survivin. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding Survivin. Methods of using these compounds for modulation of Survivin expression and for treatment of diseases associated with expression of Survivin are provided.

L'invention concerne des composés anti-sens, des compositions et des méthodes permettant la modulation de l'expression de la survivine. Les compositions comprennent des composés anti-sens, en particulier des oligonucléotides anti-sens, ciblés pour des acides nucléiques codant pour la survivine. L'invention concerne également des méthodes d'utilisation de ces composés pour la modulation d'expression de la survivine et pour le traitement de maladies associées à l'expression de la survivine.

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