A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/21 (2006.01) A61K 39/395 (2006.01) A61P 31/18 (2006.01) A61P 37/04 (2006.01)
Patent
CA 2659742
A method of treatment of HIV by inducing an immune response that includes a robust mucosal immune response. Parenteral administration of an immunogenic composition into the intestinal wall brings the composition into contact with the Peyer's patches of the gut-associated lymphoid system. Administration of multiple immunogenic compositions may track with sites or paths targeted by HIV for infection. The method of administration not only targets the most susceptible part of the host immune system to HIV, but also follows the path of entry and the spread of the naturally occurring disease.
La présente invention concerne un procédé de traitement du VIH par l'induction d'une réponse immunitaire comprenant une forte réponse immunitaire de la muqueuse. L'administration parentérale d'une composition immunogène dans la paroi de l'intestin met la composition en contact avec les plaques du système lymphoïde associé à l'intestin. L'administration de plusieurs compositions immunogènes peut localiser des sites ou des trajectoires ciblés par le VIH pour l'infection. Le procédé d'administration cible non seulement la partie la plus sensible du système immunitaire hôte au VIH, mais suit également la trajectoire de l'entrée et de la propagation de la maladie naturelle.
Karp Nelson M.
Na
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