Mosaic infectious bursal disease virus vaccines

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/40 (2006.01) A61K 39/12 (2006.01) C07K 14/08 (2006.01) C12N 7/00 (2006.01) C12N 7/04 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2379059

The invention relates to recombinant Infectious Bursal Disease Virus (IBDV) and vaccines derived thereof. The invention provides infectious recombinant Infectious Bursal Disease Virus (rIBDV) essentially incapable of growing in a cell that is not derived from a bursa cell, or an infectious rIBDV having retained at least part of the very virulent characteristics of a very virulent Infectious Bursal Disease Virus (vvIBDV).

L'invention concerne le virus recombiné de la bursite infectieuse (IBDV) et des vaccins dérivés de celui-ci. Elle porte également sur un virus recombiné de la bursite infectieuse (rIBDV), essentiellement incapable de se développer dans une cellule qui n'est pas dérivée d'une cellule de bourse séreuse, ou sur un virus de rIBDV ayant conservé au moins une partie des caractéristiques très virulentes d'un virus de bursite infectieuse (vvIBDV) très virulent.

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