Improved microbial production of indigo

C - Chemistry – Metallurgy – 12 – P

Patent

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C12P 17/10 (2006.01) C12P 1/00 (2006.01)

Patent

CA 2646494

There is provided an improved process for the biosynthetic production of indigo, the improvement comprising removing unwanted by-products such as isatin or indirubin from the broth in which such indigo is produced. Isatin can be removed by contacting the broth containing the isatin with appropriate adsorption compounds/compositions such as carbon or appropriate resins. Since isatin is the precursor of indirubin, the indirubin levels are decreased as a result of isatin removal.

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