Tubular prosthesis for external agent delivery

A - Human Necessities – 61 – F

Patent

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Details

A61F 2/06 (2006.01) A61F 2/00 (2006.01)

Patent

CA 2465677

A tubular prosthesis, which may be an endovascular prosthesis, is provided which includes a tubular member (12, 12A) (stent or stent/graft combination) and an outer covering (14) having portions sealed to the tubular member. The tubular member is impervious to a pre-determined fluid, particularly an occluding fluid, while the outer cover is pervious to the pre-determined fluid. In one aspect of the present invention, the implantation of the prosthesis allows for occluding fluid to weep from the prosthesis and into a sac of an aneurysm to cause occlusion thereof without introducing the occluding fluid into the blood stream. In this manner, a Type II failure of the prosthesis may be avoided. In other aspects of the invention, therapeutic agents may be delivered and/or a seal may be formed about the prosthesis to prevent a Type I failure.

L'invention a trait à une prothèse tubulaire, qui peut être une endoprothèse vasculaire, comprenant un élément tubulaire (12, 12A) (stent ou combinaison stent/greffon) et une enveloppe extérieure (14) dont certaines parties sont solidaires de l'élément tubulaire. L'élément tubulaire est imperméable à un fluide prédéterminé, en particulier à un fluide d'occlusion, tandis que l'enveloppe extérieure est perméable audit fluide prédéterminé. Dans un aspect de la présente invention, l'implantation de la prothèse permet au fluide d'occlusion de filtrer de la prothèse dans un sac anévrismal pour en provoquer l'occlusion, et ce sans qu'il soit nécessaire d'introduire le fluide d'occlusion dans le flux sanguin. Cette technique permet d'éviter une défaillance de type II de la prothèse. Dans d'autres aspects de l'invention, des agents thérapeutiques peuvent être administrés, et/ou un joint hermétique peut être formé autour de la prothèse pour éviter une défaillance de type I.

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