Method for racemate splitting of 2-hydroxypropionic acids

Details Method for racemate splitting of 2-hydroxypropionic acids Method for racemate splitting of 2-hydroxypropionic acids

C - Chemistry, Metallurgy

07

C

C07C 51/487 (2006.01) C07B 57/00 (2006.01) C07C 59/48 (2006.01) C07C 59/64 (2006.01)

Patent

CA 2347758

The invention relates to racemate splitting of 2-hydroxypropionic acids by reacting racemic acid with an optically active base and subsequently separating a diastereomeric salt from the acid and the base. The invention is characterized in that t-(4-chlorophenyl)ethylamine is used as optically active base.

L'invention concerne un procédé de fission racémique d'acides 2-hydroxypropioniques. Ce procédé consiste à faire réagir l'acide racémique avec une base optiquement active puis à séparer un sel diastéréomère à partir de l'acide et de la base. L'invention est caractérisée en ce que l'on utilise un 1-(4-chlorophényl)éthylamine comme base optiquement active.

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