Method and composition employing (2r,4s) itraconazole

Details Method and composition employing (2r,4s) itraconazole Method and composition employing (2r,4s) itraconazole

A - Human Necessities

61

K

A61K 31/495 (2006.01)

Patent

CA 2154777

Methods and compositions are disclosed utilizing the optically pure (2R,4S) isomer of itraconazole. This compound is a potent drug for the treatment of local and systemic fungal, yeast, and dermatophyte infections, while avoiding the concomitant liability of adverse effects associated with the racemic mixture of intraconazole.

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