In vivo treatment of mammalian tissue with a metabotropic...

Details In vivo treatment of mammalian tissue with a metabotropic... In vivo treatment of mammalian tissue with a metabotropic...

A - Human Necessities

61

K

A61K 31/195 (2006.01) A61K 31/00 (2006.01) A61K 31/196 (2006.01) A61K 31/198 (2006.01)

Patent

CA 2178680

A method and composition for in vivo reducing the deleterious effect of traumatic CNS tissue injury by applying to said tissue a therapeutically effective amount of a metabotropic glutamate receptor agonist, preferably, trans-1-amino-1,3- cyclopentanedicarboxylic acid. The metabotropic glutamate receptor agonist preferably activates a mGluR subtype, for example the mGluR-1 subtype.

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