Hybrid streptokinases with fibrin binding domains and...

Details Hybrid streptokinases with fibrin binding domains and... Hybrid streptokinases with fibrin binding domains and...

C - Chemistry, Metallurgy

12

N

195/39, 195/1.2,

C12N 15/74 (2006.01) C07K 14/315 (2006.01) C12N 1/21 (2006.01) C12N 9/68 (2006.01) C12N 9/70 (2006.01) C12N 15/58 (2006.01) C12N 15/72 (2006.01)

Patent

CA 2016236

Abstract of the Disclosure Compositions and methods for the synthesis of hybrid streptokinase with fibrin binding domains based on gene fusion technology. Recombinant DNA methods have been used to fuse gene segments for streptokinase and for fibrin-binding domains and express the fused gene in prokaryotic microorganisms, and the respective expressed protein is subsequently obtained by biotechnologic fermentation for the purpose of use in clinical medicine.

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