Method and devices for lyophilizing, reconstituting, and...

A - Human Necessities – 61 – M

Patent

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Details

A61M 5/28 (2006.01) A61M 5/24 (2006.01) A61M 5/31 (2006.01) A61M 5/50 (2006.01)

Patent

CA 2585139

The invention relates to a method and a device for lyophilizing, reconstituting, and administering a reconstituted agent. Said device comprises an elongate housing (3) with a forward housing end (6) located on the discharge side and a rear housing end (7) which lies opposite the forward housing end (6). A first chamber (1) containing a lyophilisate is disposed in the area of the forward housing end (6) inside the housing. Said first chamber (1) is tightly sealed at the end that faces the forward housing end (6) by means of a removable closure (9) while being tightly sealed in the direction of the rear housing end (7) with the aid of a plunger (11). A second chamber (2) that is connected to the ambient atmosphere via at least one opening (13) is embodied or positioned in the area of the rear housing end (7) inside the housing (3). Said opening (13) is closed by means of a membrane (14) that is permeable to gas but not to bacteria.

L'invention concerne un procédé et un dispositif de lyophilisation, de reconstitution et d'administration d'un principe actif reconstituant. Ce dispositif comprend un boîtier allongé (3) doté d'une extrémité (6) avant côté délivrance et d'une extrémité (7) arrière opposée. Le boîtier (3) abrite dans la zone de l'extrémité (6) avant une première chambre (1) qui contient un lyophilisat et qui est fermée hermétiquement à son extrémité tournée vers l'extrémité boîtier (6) avant par un couvercle (9) amovible et en direction de l'extrémité boîtier (7) arrière par un piston (11). Une deuxième chambre (2) qui est formée ou placée dans la zone de l'extrémité boîtier (7) arrière du boîtier (3), est reliée à l'atmosphère environnant par au moins un orifice (13). Cet orifice (13) est fermé par une membrane (14) perméable au gaz mais pas aux bactéries.

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