Pyrazole compounds, pharmaceutical compositions, and methods...

C - Chemistry – Metallurgy – 07 – D

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C07D 487/04 (2006.01) A61K 31/435 (2006.01) A61K 31/505 (2006.01) A61P 25/28 (2006.01)

Patent

CA 2415182

Pyrazole compounds represented by the formula (I), are described. The pyrazole compounds and pharmaceutical compositions containing them may be used in inhibiting ERAB or HADH2 activity and in treating ERAB, HADH2 or amyloid- .beta. mediated diseases and conditions.

L'invention concerne des composés de pyrazole représentés par la formule (I). Ces composés de pyrazole et les compositions pharmaceutiques les contenant peuvent être utilisés dans l'inhibition de l'activité ERAB ou HADH2 et dans le traitement de maladies ou de conditions induites par ERAB, HADH2 ou un amyloïde-.beta..

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