Cytotoxic factor linked with multiple sclerosis and...

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/68 (2006.01) A61K 38/17 (2006.01) A61K 39/395 (2006.01) C07K 14/47 (2006.01) C12Q 1/18 (2006.01) G01N 33/50 (2006.01) G01N 33/566 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2142557

Facteur gliotoxique, à l'état isolé ou purifié, caractérisé en ce qu'il possède, une activité toxique vis-à-vis des cellules astrocytaires humaines ou animales, ayant pour effet une désorganisation cytomorphologique de leur réseau de filaments intermédiaires, et/ou une dégradation des protéines desdits filaments intermédiaires, et/ou une mort cellulaire notamment, par apoptose.

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