Cloning and characterization of slc26a7 and slc26a9 anion...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/12 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) C12P 21/02 (2006.01) C12Q 1/68 (2006.01) G01N 33/566 (2006.01)

Patent

CA 2477566

Isolated nucleic acids encoding SLC26A7 and SLC26A9 anion transporter polypeptides, recombinantly expressed SLC26A7 and SLC26A9 anion transporter polypeptides, heterologous expression systems for recombinant expression of SLC26A7 and SLC26A9 anion transporter polypeptides, assay methods employing the same, and methods for modulation of anion transport activity.

L'invention concerne des acides nucléiques codant pour des polypeptides transporteurs d'anions SLC26A7 et SLC26A9, des polypeptides transporteurs d'anions exprimés par recombinaison SLC26A7 et SLC26A9, des systèmes d'expression hétérologue destinés à l'expression recombinante de polypeptides transporteurs d'anions SLC26A7 et SLC26A9, des procédés de tests employant ces polypeptides ainsi que des procédés de modulation de l'activité de transport d'anions.

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