Activating hydroxyl groups of polymeric carriers using...

Details Activating hydroxyl groups of polymeric carriers using... Activating hydroxyl groups of polymeric carriers using...

C - Chemistry, Metallurgy

12

N

C12N 11/10 (2006.01) C12N 11/08 (2006.01) G01N 33/543 (2006.01) G01N 33/545 (2006.01) G01N 33/548 (2006.01)

Patent

CA 2075719

2075719 9203544 PCTABS00011 The invention relates to a method of binding biologically active organic ligands to hydroxyl groups of polymeric carriers. The method involves bringing 4-fluorobenzenesulfonyl chloride into reactive contact with the hydroxyl groups of polymeric carriers in such a manner to form sulfonate groups in place of the hydroxyl groups. The ligand is then brought into reactive contact with the hydroxyl groups of polymeric carrier to replace the sulfonate groups reacted with the organic ligand.

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