Improved methods for transfecting t cells

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/87 (2006.01) C07K 16/28 (2006.01) C12N 5/10 (2006.01) C12N 15/67 (2006.01) C12N 15/85 (2006.01) A61K 35/14 (2006.01) A61K 48/00 (2006.01)

Patent

CA 2220226

A method for transfecting T cells with a nucleic acid molecule comprising a gene such that the gene is expressed in the T cells is described. The T cells are stimulated and proliferating prior to introduction of the nucleic acid molecule.

L'invention se rapporte à un procédé de transfection des lymphocytes T avec une molécule d'acide nucléique comprenant un gène de sorte que le gène soit exprimé dans les lymphocytes T. Les lymphocytes T sont stimulés et leur prolifération est induite avant l'introduction de la molécule d'acide nucléique.

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