Hydroxy substituted amides for the treatment of alzheimer's...

Details Hydroxy substituted amides for the treatment of alzheimer's... Hydroxy substituted amides for the treatment of alzheimer's...

A - Human Necessities

61

K

A61K 31/421 (2006.01) A61K 31/165 (2006.01) A61K 31/18 (2006.01) A61K 31/195 (2006.01) A61K 31/38 (2006.01) A61K 31/381 (2006.01) A61K 31/404 (2006.01) A61K 31/426 (2006.01) A61K 31/437 (2006.01) A61K 31/445 (2006.01) A61K 31/495 (2006.01) A61K 31/537 (2006.01) A61K 31/54 (2006.01) A61K 45/06 (2006.01) A61P 25/28 (2006.01) A61P 43/00 (2006.01)

Patent

CA 2465316

The present invention is a method of treating Alzheimer's disease, and other diseases, and/or inhibiting beta-secretase enzyme, and/or inhibiting deposition of A beta peptide in a mammal, by use of known compounds of Formula (I), wherein, A, R, J, and n are as defined herein.

L'invention concerne une méthode de traitement de la maladie d'Alzheimer, entre autres maladies, et/ou d'inhibition de la bêta-sécrétase, et/ou d'inhibition du dépôt d'un A-bêta peptide chez un mammifère. Cette méthode consiste à utiliser des composés connus de la formule (I) dans laquelle, A, R, J, et n sont tels que définis dans le descriptif.

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