A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/28 (2006.01) A61K 38/26 (2006.01) A61P 3/00 (2006.01) A61P 9/00 (2006.01) A61P 11/00 (2006.01) A61P 25/28 (2006.01) A61P 31/00 (2006.01) A61P 31/04 (2006.01) A61P 31/06 (2006.01) A61P 31/18 (2006.01) A61P 31/20 (2006.01) A61P 35/00 (2006.01) A61P 37/00 (2006.01)
Patent
CA 2699035
The present invention is directed to the use of the peptide compound Glu-Ala- Glu-Asp- Leu-Gln-Val-Gly-Gln- Val-Glu-Leu-Gly-Gly-Gly-Pro-Gly-Ala-Gly-Ser-Leu-Gln-Pro-Leu- Ala-Leu-Glu-Gly- Ser-Leu-Gln-OH as a therapeutic agent for the prophylaxis and/or treatment of cancer, autoimmune diseases, fibrotic diseases, inflammatory diseases, neurodegenerative diseases, infectious diseases, lung diseases, heart and vascular diseases and metabolic diseases. Moreover the present invention relates to pharmaceutical compositions preferably in form of a lyophilisate or liquide buffer solution or artificial mother milk formulation or mother milk substitute containing the peptide Glu-Ala-Glu-Asp-Leu-Gln-Val- Gly-Gln-Val- Glu-Leu-Gly-Gly-Gly-Pro-Gly-Ala- Gly-Ser-Leu-Gln-Pro-Leu-Ala-Leu-Glu-Gly-Ser-Leu- Gln-OH optionally together with at least one pharmaceutically acceptable carrier, cryoprotectant, lyoprotectant, excipient and/or diluent.
La présente invention porte sur l'utilisation du composé peptidique Glu-Ala-Glu-Asp-Leu-Gln-Val-Gly-Gln-Val-Glu-Leu-Gly-Gly-Gly-Pro-Gly-Ala-Gly-Ser-Leu-Gln-Pro-Leu-Ala-Leu-Glu-Gly-Ser-Leu-Gln-OH en tant qu'agent thérapeutique pour la prophylaxie et/ou le traitement du cancer, des maladies auto-immunes, des maladies fibrosantes, des maladies inflammatoires, des maladies dégénératives du système nerveux, des maladies infectieuses, des maladies pulmonaires, des maladies cardiaques et vasculaires et des maladies métaboliques. De plus, la présente invention porte sur des compositions pharmaceutiques, de préférence sous forme de lyophilisat ou de solution tampon liquide ou de formulation de lait maternel artificiel ou de substitut de lait maternel contenant le peptide Glu-Ala-Glu-Asp-Leu-Gln-Val-Gly-Gln-Val-Glu-Leu-Gly-Gly-Gly-Pro-Gly-Ala-Gly-Ser-Leu-Gln-Pro-Leu-Ala-Leu-Glu-Gly-Ser-Leu- GIn-OH facultativement conjointement avec au moins un support, un cryoprotecteur, un lyoprotecteur, un excipient et/ou un diluant acceptable du point de vue pharmaceutique.
Bacher Gerald
Bevec Dorian
Cavalli Fabio
Cavalli Vera
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Mondobiotech Laboratories Ag
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