C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 7/00 (2006.01) A61K 39/125 (2006.01) A61K 39/295 (2006.01) A61P 31/14 (2006.01) C07K 16/10 (2006.01) G01N 33/543 (2006.01) G01N 33/569 (2006.01)
Patent
CA 2579141
The present invention relates to a novel, isolated and purified hemorrhagic feline calicivirus FCV-DD1. The invention further embraces monovalent and multivalent vaccines containing the new FCV-DD1 strain. In addition, the invention encompasses methods of protecting felines against infection or preventing disease caused by feline calicivirus alone or in addition to other pathogens that comprises administering to the felines an immunologically effective amount of the monovalent and multivalent vaccines described herein. Also, the invention concerns methods for diagnosing or detecting the hemorrhagic feline calicivirus in a susceptible host, asymptomatic carrier and the like by detecting the presence of feline calicivirus FCV-DD1 or antibodies raised or produced against feline calicivirus FCV-DD1 antigen.
L'invention concerne un nouveau calicivirus félin hémorragique purifié et isolé (FCV-DD1). L'invention concerne également des vaccins monovalents et multivalents contenant la nouvelle souche de FCV-DD1. L'invention concerne encore des méthodes permettant de protéger les félins contre l'infection ou de prévenir la maladie causée par le calicivirus, seul ou associé à d'autres agents pathogènes, cette méthode consistant à administrer aux félins une quantité immunologiquement efficace de ces vaccins monovalents ou multivalents. L'invention concerne enfin des méthodes permettant de diagnostiquer ou de détecter le calicivirus félin hémorragique chez un hôte réceptif, un porteur asymptomatique ou analogue, par détection de la présence du calicivirus félin FCV-DD1 ou d'anticorps élevés ou produits contre un antigène du FCV-DD1.
Hess Jennifer
Huang Chengjin
Boehringer Ingelheim Vetmedica Inc.
Fetherstonhaugh & Co.
Wyeth
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