Synthesis and antimicrobial activity of novel dicationic...

C - Chemistry – Metallurgy – 07 – D

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C07D 409/12 (2006.01) A61K 31/34 (2006.01) A61K 31/40 (2006.01) A61K 31/443 (2006.01) A61K 31/4439 (2006.01) A61K 31/4709 (2006.01) C07D 215/12 (2006.01) C07D 307/10 (2006.01) C07D 307/14 (2006.01) C07D 307/34 (2006.01) C07D 307/52 (2006.01) C07D 333/20 (2006.01) C07D 401/12 (2006.01) C07D 405/12 (2006.01)

Patent

CA 2425135

The present invention relates to novel 2,5-bis{[alkyl (or aryl) imino] aminophenyl} furans and thiophenes of the general formula (I) in which R1, R2, R3 and R4 are each independently selected from the group consisting of H, alkyl, alkoxy, halide, and alkylhalide groups; R5 is H, alkyl or aryl; R6 is H, alkyl, aryl, or NR7R8, in which R7 and R8 are each independently selected from the group consisting of H, alkyl and aryl; and X is O, S or NR9, in which R9 is H or alkyl, and to the use of such compounds.

L'invention concerne de nouveaux thiophènes et furannes 2,5-bis{[alkyl(ou aryl) imino] aminophényl} représentés par la formule générale (I) dans laquelle R¿1?, R¿2?, R¿3? et R¿4? sont individuellement sélectionnés dans le groupe constitué par H, alkyle, alcoxy, halogénure, et des groupes d'alkylhalogénure; R¿5? représente H, alkyle ou aryle; R6 représente H, alkyle, aryle, ou NR¿7?R¿8?, dans lequel R¿7 ?et R¿8? sont individuellement sélectionnés dans le groupe constitué par H, alkyle et aryle; et X représente O, S ou NR¿9?, dans lequel R¿9? représente H ou alkyle ; L'invention concernant par ailleurs l'utilisation de ces composés.

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