Compositions and methods for increasing packaging and yields...

Details Compositions and methods for increasing packaging and yields... Compositions and methods for increasing packaging and yields...

C - Chemistry, Metallurgy

12

N

C12N 15/86 (2006.01) C12N 15/861 (2006.01) A61K 48/00 (2006.01)

Patent

CA 2392537

A recombinant adenoviral vector which has multiple adenovirus packaging domains is provided. This vector has advantages over conventional adenoviral vectors in packaging plasmid vectors into adenoviral capsids. Methods of making and using this vector are described.

L'invention concerne un vecteur d'adénovirus de recombinaison possédant des domaines multiples d'encapsidation d'adénovirus. Ce vecteur présente des avantages par rapport à des vecteurs d'adénovirus classiques, étant donné qu'il permet d'encapsider des vecteurs de plasmides dans des capsides adénovirales. Elle concerne également des procédés de préparation et de d'utilisation de ce vecteur.

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