Peptides capable of modulating immune response

Details Peptides capable of modulating immune response Peptides capable of modulating immune response

C - Chemistry, Metallurgy

07

K

C07K 14/705 (2006.01) A61K 38/18 (2006.01) A61P 37/06 (2006.01) C07K 14/725 (2006.01) C07K 14/74 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2486545

Provided are peptides capable of inhibiting proliferation of peripheral blood mononuclear cells (PBMCs) derived from HLA class II alpha 2 chain. Furthermore, peptides capable of inhibiting proliferation of peripheral blood mononuclear cells (PBMCs) derived from T-cell immune response cDNA 7 (TIRC7) costimulatory molecule are described. Compositions comprising such peptides and their use for the treatment of immune diseases are provided.

L'invention concerne des peptides capables d'inhiber la prolifération de cellules mononuclées de sang périphérique (PBMC) dérivées de la chaîne alpha 2 de classe II du système HLA. Elle se rapporte aussi à des peptides capables d'inhiber la prolifération de cellules mononuclées de sang périphérique (PBMC) dérivées de la molécule costimulatrice d'un ADNc 7 à réponse immunitaire spécifique aux lymphocyte T (TIRC7). Cette invention porte également sur des compositions contenant ces peptides et sur leur utilisation dans le traitement de maladies immunitaires.

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