Transdermal nitroglycerin patch with penetration enhancers

Details Transdermal nitroglycerin patch with penetration enhancers Transdermal nitroglycerin patch with penetration enhancers

A - Human Necessities

61

M

A61M 37/00 (2006.01) A61K 9/70 (2006.01) A61K 31/04 (2006.01) A61K 31/21 (2006.01) A61K 47/10 (2006.01) A61K 47/12 (2006.01) A61K 47/14 (2006.01) A61K 47/22 (2006.01)

Patent

CA 2064845

2064845 9102553 PCTABS00003 A transdermal nitroglycerin patch exhibiting superior nitroglycerin skin penetrating characteristics comprising a percutaneous penetration enhancer is disclosed, wherein the penetration enhancer may be one or more of N-methyl-2-pyrrolidone, oleic acid, oleyl alcohol, linoleic acid, isopropyl linoleate, azone and butanediol. Also disclosed is a transdermal patch design comprising two concentric rings, wherein the concentrations of nitroglycerin and the permeability enhancer are varied.

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