Use of (+)-tramadol, o-demethyltramadol or...

A - Human Necessities – 61 – K

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Details

A61K 31/137 (2006.01) A61K 31/135 (2006.01) A61P 13/10 (2006.01)

Patent

CA 2386381

The invention relates to the use of (+)-tramadol or O-demethyl-tramadol, in particular, (+)-O-demethyltramadol, O-desmethyl-N-mono-desmethyl-tramadol, in particular, (+)-O-desmethyl-N-mono-desmethyl-tramadol. According to the invention, these compounds are used as free bases and/or in the form of physiologically compatible salts for producing a medicament that is used to treat increased desire to urinate or urinary incontinence. The invention also relates to corresponding medicaments and to methods for treating increased desire to urinate or urinary incontinence.

L'invention concerne l'utilisation, pour préparer un médicament pour traiter la strangurie accrue et l'incontinence urinaire, de (+)-tramadol ou de O-déméthyltramadol, notamment de (+)-O-déméthyltramadol, de O-desméthyl-N-mono-desméthyl-tramadol, notamment (+)-O-desméthyl-N-mono-desméthyl-tramadol. Selon l'invention, ces composés s'utilisent sous forme de bases et/ou de sels physiologiquement tolérables. L'invention concerne en outre des médicaments correspondants et des procédés pour traiter la strangurie accrue et l'incontinence urinaire.

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