Imidazoles

Details Imidazoles Imidazoles

C - Chemistry, Metallurgy

07

D

C07D 233/84 (2006.01) A61K 31/415 (2006.01) A61K 31/44 (2006.01) A61K 31/535 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 405/12 (2006.01) C07D 413/12 (2006.01)

Patent

CA 2078208

2078208 9113876 PCTABS00007 Imidazole derivates of general formula (II) in which R1 is hydrogen or one or more substituents, k is 0, 1 or 2, Q is a straight or branched alkylene group and Z is hydrogen or a substituent group and pharmaceutically acceptable salts thereof possess useful pharmacological properties as inhibitors of acyl coenzyme-A: cholesterol-o-acyl transferase and as inhibitors of the binding of thromboxane TXA2 to its receptors, and are useful in therapy.

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